Product Name: GS-441524 Sterile Injection
Strength: 20mg/ml × 6ml; 20mg/ml × 8ml; 20mg/ml × 10ml; 30mg/ml × 6ml; 30mg/ml × 8ml; 30mg/ml ×10ml
Package: 10 PCS/box
For Use In: Cats
Actions & Indications:
For the treatment of naturally occurring feline infectious peritonitis in cats, including:
Effusive (wet) FIP
Non-effusive (dry) FIP
FIP with ocular or neurological involvement (dose adjustment may be required)
Dosage:
Recommended Dosage
4.0 mg/kg body weight, once every 24 hours, by subcutaneous injection
Treatment Duration
At least 12 consecutive weeks
|
Body weight (kg) |
Dose per Administration(mg) |
Volume for 20mg/ml (ml) |
Volume for 30mg/ml (ml) |
| 1.0-2.0 | 4-8 | 0.2-0.4 | 0.13-0.27 |
| 2.0-3.0 | 8-12 | 0.4-0.6 | 0.27-0.40 |
| 3.0-40 | 12-16 | 0.6-0.8 | 0.40-0.53 |
| 4.0-5.0 | 16-20 | 0.8-1.0 | 0.53-0.67 |
| 5.0-6.0 | 20-24 | 1.0-1.2 | 0.67-0.80 |
| 6.0-7.0 | 24-28 | 1.2-14 | 0.80-0.93 |
| >7.0 | Calculate by weight | Proportional | Proportional |
Special Dosage Instructions:
Forcatswithocular orneurologicalsigns,adosageof4.0 mg/kgorhigherisrecommendedunder veterinarysupervision,withconsiderationofextendedtreatmentduration.
Treatment Response:
Accordingtoclinicalstudies (Pedersen et al., 2019):
Bodytemperaturereturnsto normal within 12–36hours in most cats
Appetite,activity level, andbody weight improve significantly within 1–2 weeks
Abdominalorthoracic effusion resolves graduallywithin 1–2 weeks
Serumalbumin andA/Gratio normalizewithin 8–10 weeks
Over80%ofcats completing 12weeksormore of treatment achieve long-term
Adverse Reactions:
InjectionSiteReactions
Localswelling, scabbing,or ulceration,mostcommon in the first few weeks of treatment
Incidenceapproximately60%,withopensores occurringin about25%ofcases
Usuallyhealwithin2weekswithsupportivecare(local cleaning, rotation of injection sites)
Precautions:
1.This is a prescription drug and must be used under veterinary supervision
2.Regular monitoring of body weight, serum albumin, A/G ratio, and complete blood count is recommended during treatment
3.For cats with ocular or neurological signs, individualized treatment plans should be developed under specialist supervision
4.The injectable solution has a low pH (approximately 1.5) and may cause transient pain upon injection;rotation of injection sites is recommended
5.Not recommended for use in pregnant or lactating cats due to insufficient safety data
Discontinuation:
After treatment completion, observation for at least 3 months is recommended. Veterinary re-evaluation is advised if any of the following occur:
Weight loss
Fever
Decreased appetite
Lethargy
Abdominal distension or dyspnea
For animal use only.