Product Name: Fluralaner Topical Solution (Pour-On)
Indication: For the prevention and treatment of infestations caused by New World screwworm (Cochliomyia hominivorax) larvae (myiasis) and treatment and control of cattle fever tick (Rhipicephalus microplus) in beef cattle 2 months of age and older and replacement dairy heifers less than 20 months of age.
For Use In:Beef cattle 2 months of age and older; replacement dairy heifers less than 20 months of age
Not for use in: Bulls intended for breeding 1 year of age and older, dairy calves, veal calves, and female dairy cattle 20 months of age or older (including dry dairy cows).
Dosage:
|
Parameter
|
Value
|
|
Dosage
|
1 mL per 44.1 lbs (1 mL per 20 kg) body weight
|
|
Equivalent
|
2.5 mg fluralaner per kg body weight
|
|
Route
|
Topical (pour-on)
|
|
Frequency
|
Single administration
|
|
Body Weight (lbs)
|
Body Weight (kg)
|
Dose Volume (mL)
|
|
220
|
100
|
5
|
|
330
|
150
|
7.5
|
|
440
|
200
|
10
|
|
550
|
250
|
12.5
|
|
660
|
300
|
15
|
|
770
|
350
|
17.5
|
|
880
|
400
|
20
|
|
990
|
450
|
22.5
|
|
1100
|
500
|
25
|
|
1320
|
600
|
30
|
For body weight above 1320 lbs (600 kg): Add 2.5 mL for each additional 110 lbs (50 kg).
Administration Instructions
Apply in a narrow strip along the dorsal midline from the withers to the base of the tail.
1.Hold the bottle upright and at eye level – slowly squeeze the bottle to fill the dosing chamber to the selected mark
2.Pour the measured volume along the dorsal midline from withers to tail base
3.A small amount of liquid will remain on the chamber walls (chamber is calibrated to account for this)
4.Avoid squeezing the container while pouring from the dosing chamber
Mechanism of Action
Fluralaner belongs to the class of isoxazoline-substituted benzamide derivatives. It inhibits the arthropod
nervous system by antagonizing ligand-gated chloride channels (GABA-receptor and glutamate-receptor), leading to uncontrolled nerve activity and death of parasites.
Withdrawal Period
|
Condition
|
Withdrawal Period
|
|
General
|
98 days post-treatment
|
|
Continuous exposure to ≥60°F (≥15.5°C) after treatment
|
44 days post-treatment
|
Warning: Violative residues may result if cattle are exposed to temperatures below 60°F after administration and are slaughtered at 44 days.
Environmental Precautions
Do not contaminate ponds, waterways, or ditches with the product or used containers
Dispose of empty containers according to local regulations
This product is toxic to aquatic organisms
Package:
100ml, 500ml, 1L, 5L, 20L HDPE bottles
Storage:
Store tightly sealed below 30°C, protected from light. Do not freeze.
Shelf life: 2 years(opened: use within 6 months)
For animal use only.
